Jalan Cerita:
Harley Quinn joins forces with a singer, an assassin and a police detective to help a young girl who had a hit placed on her after she stole a rare diamond from a crime lord.

Pemain:

Margot Robbie Harley Quinn

Rosie Perez Renee Montoya

Mary Elizabeth Winstead Helena Bertinelli / Huntress

Jurnee Smollett Dinah Lance / Black Canary

Ewan McGregor Roman Sionis