Jalan Cerita:
During a space voyage, four scientists are altered by cosmic rays: Reed Richards gains the ability to stretch his body; Sue Storm can become invisible; Johnny Storm controls fire; and Ben Grimm is turned into a super-strong … thing. Together, these "Fantastic Four" must now thwart the evil plans of Dr. Doom and save the world from certain destruction.

Pemain:

Ioan Gruffudd Reed Richards / Mr. Fantastic

Jessica Alba Sue Storm / Invisible Woman

Chris Evans Johnny Storm / Human Torch

Michael Chiklis Ben Grimm / The Thing

Julian McMahon Victor von Doom / Doctor Doom