Jalan Cerita:
Eight years after the third film, the OSS has become the world's top spy agency, while the Spy Kids department has since become defunct. A retired spy Marissa is thrown back into the action along with her stepchildren when a maniacal Timekeeper attempts to take over the world. In order to save the world, Rebecca and Cecil must team up with their hated stepmother. Carmen and Juni have since also grown up and will provide gadgets to them.

Pemain:

Jessica Alba Marissa Wilson

Joel McHale Wilbur Wilson

Rowan Blanchard Rebecca Wilson

Mason Cook Cecil Wilson

Jeremy Piven Danger D'Amo / Tick Tock / Time Keeper